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KMID : 0613820050150020242
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Journal of Life Science
2005 Volume.15 No. 2 p.242 ~ p.247
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The Effects of Hijikia fusiforme on Serum Lipid Levels in Ovariectomized Rats
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Kim Jeang-Yub
Kim Mi-Hyang
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Abstract
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The aim of this study was evaluated the effect of biological activity of Hijikia fusiforme (HF). To investigate the effects of biological activity of HF ethanol extracts, Sprague-Dawley female rats were randomly assigned to the following groups: sham-operated rats (Sham), ovariectomized control rats (OVX-control), ovariectomized rats supplemented ethanol extracts of HF at 50 ㎎/㎏ bw/day (OVX-HF50), ovariectomized rats supplemented ethanol extracts of HF at 200 ㎎/㎏ bw/day (OVX-HF200). HF ethanol extracts were orally supplemented at the level of 1 mL per day. The body weight gain, food intake and food efficiency ratio were not significantly different between groups. Although total-cholesterol and triglyceride were increased in the ovariectomized control, supplementation with the HF extracts decreased the levels. And HDL-cholesterol levels were significantly increased after supplementation with the HF extracts (p＜0.05). According to these results, we could known the effects biological activity of Hijikia fusiforme. Consequently, we expect the effects of Hijikia fusiforme extract on cardiovascular diseases aging coming from postmenopausal.
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